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Structural constraints on autoprocessing of the human nucleoporin Nup98

Nucleoporin Nup98, a 98-kDa protein component of the nuclear pore complex, plays an important role in both protein and RNA transport. During its maturation process, Nup98 undergoes post-translational autoproteolysis, which is critical for targeting to the NPC. Here we present high-resolution crystal...

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Detalhes bibliográficos
Main Authors: Sun, Yixin, Guo, Hwai-Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248301/
https://ncbi.nlm.nih.gov/pubmed/18287282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073311808
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