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Structural constraints on autoprocessing of the human nucleoporin Nup98
Nucleoporin Nup98, a 98-kDa protein component of the nuclear pore complex, plays an important role in both protein and RNA transport. During its maturation process, Nup98 undergoes post-translational autoproteolysis, which is critical for targeting to the NPC. Here we present high-resolution crystal...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2248301/ https://ncbi.nlm.nih.gov/pubmed/18287282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073311808 |
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