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The P granule component PGL-1 promotes the localization and silencing activity of the PUF protein FBF-2 in germline stem cells

In the C. elegans germline, maintenance of undifferentiated stem cells depends on the PUF family RNA-binding proteins FBF-1 and FBF-2. FBF-1 and FBF-2 are 89% identical and are required redundantly to silence the expression of mRNAs that promote meiosis. Here we show that, despite their extensive se...

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Sonraí Bibleagrafaíochta
Main Authors: Voronina, Ekaterina, Paix, Alexandre, Seydoux, Geraldine
Formáid: Artigo
Teanga:Inglês
Foilsithe: Company of Biologists 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445306/
https://ncbi.nlm.nih.gov/pubmed/22991439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.083980
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