Recognition of dextran-superparamagnetic iron oxide nanoparticle conjugates (Feridex) via macrophage scavenger receptor charged domains

Dextran-coated superparamagnetic iron oxide nanoparticles (dextran-SPIO conjugates) offer the attractive possibility of enhancing MRI imaging sensitivity so that small or diffuse lesions can be detected. However, systemically injected SPIO are rapidly removed by macrophages. We engineered embryonic...

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Detalhes bibliográficos
Main Authors: Chao, Ying, Makale, Milan, Karmali, Priya Prakash, Sharikov, Yuriy, Tsigelny, Igor, Merkulov, Sergei, Kesari, Santosh, Wrasidlo, Wolf, Ruoslahti, Erkki, Simberg, Dmitri
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444675/
https://ncbi.nlm.nih.gov/pubmed/22515422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200685a
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