Mechanisms of complement activation by dextran-coated superparamagnetic iron oxide (SPIO) nanoworms in mouse versus human serum

BACKGROUND: The complement system is a key component of innate immunity implicated in the neutralization and clearance of invading pathogens. Dextran coated superparamagnetic iron oxide (SPIO) nanoparticle is a promising magnetic resonance imaging (MRI) contrast agent. However, dextran SPIO has been...

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Detalhes bibliográficos
Publicado no:Part Fibre Toxicol
Main Authors: Banda, Nirmal K, Mehta, Gaurav, Chao, Ying, Wang, Guankui, Inturi, Swetha, Fossati-Jimack, Liliane, Botto, Marina, Wu, LinPing, Moghimi, Seyed Moein, Simberg, Dmitri
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247556/
https://ncbi.nlm.nih.gov/pubmed/25425420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-014-0064-2
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