Evaluation of dihydrofolate reductase and dihydropteroate synthetase genotypes that confer resistance to sulphadoxine-pyrimethamine in Plasmodium falciparum in Haiti

BACKGROUND: Malaria caused by Plasmodium falciparum infects roughly 30,000 individuals in Haiti each year. Haiti has used chloroquine (CQ) as a first-line treatment for malaria for many years and as a result there are concerns that malaria parasites may develop resistance to CQ over time. Therefore...

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Hlavní autoři: Carter, Tamar E, Warner, Megan, Mulligan, Connie J, Existe, Alexander, Victor, Yves S, Memnon, Gladys, Boncy, Jacques, Oscar, Roland, Fukuda, Mark M, Okech, Bernard A
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444377/
https://ncbi.nlm.nih.gov/pubmed/22889367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-275
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