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Regulation and physiological roles of the calpain system in muscular disorders

Calpains, a family of Ca(2+)-dependent cytosolic cysteine proteases, can modulate their substrates' structure and function through limited proteolytic activity. In the human genome, there are 15 calpain genes. The most-studied calpains, referred to as conventional calpains, are ubiquitous. Whil...

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Hlavní autoři: Sorimachi, Hiroyuki, Ono, Yasuko
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444232/
https://ncbi.nlm.nih.gov/pubmed/22542715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs157
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