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Differential Expression of Ly6C and T-bet Distinguish Effector and Memory Th1 CD4(+) Cell Properties during Viral Infection

CD4(+) T cells differentiate into multiple effector types, but it is unclear how they form memory T cells during infection in vivo. Profiling virus-specific CD4(+) T cells revealed that effector cells with T helper 1 (Th1) or T follicular helper (Tfh) cell characteristics differentiated into memory...

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Detalhes bibliográficos
Main Authors: Marshall, Heather D., Chandele, Anmol, Jung, Yong Woo, Meng, Hailong, Poholek, Amanda C., Parish, Ian A., Rutishauser, Rachel, Cui, Weiguo, Kleinstein, Steven H., Craft, Joe, Kaech, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444169/
https://ncbi.nlm.nih.gov/pubmed/22018471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.08.016
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