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Inflammation Directs Memory Precursor and Short-Lived Effector CD8(+) T Cell Fates via the Graded Expression of T-bet Transcription Factor
As acute infections resolve, effector CD8 T cells differentiate into IL-7R(lo) short-lived effector cells (SLECs) and IL-7R(hi) memory precursor effector cells (MPECs) capable of generating long-lived memory CD8 T cells. Using another SLEC marker, KLRG1, we found that KLRG1(hi) effector cells began...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2034442/ https://ncbi.nlm.nih.gov/pubmed/17723218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.07.010 |
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