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Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development

The trace metal copper (Cu) plays an essential role in biology as a cofactor for many enzymes that include Cu, Zn superoxide dismutase, cytochrome oxidase, ceruloplasmin, lysyl oxidase, and dopamine β-hydroxylase. Consequently, Cu transport at the cell surface and the delivery of Cu to intracellular...

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Bibliografiske detaljer
Main Authors: Lee, Jaekwon, Prohaska, Joseph R., Thiele, Dennis J.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC34440/
https://ncbi.nlm.nih.gov/pubmed/11391005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.111058698
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