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Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals

Cisplatin is a chemotherapeutic drug used to treat a variety of cancers. Both intrinsic and acquired resistance to cisplatin, as well as toxicity, limit its effectiveness. Molecular mechanisms that underlie cisplatin resistance are poorly understood. Here we demonstrate that deletion of the yeast CT...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ishida, Seiko, Lee, Jaekwon, Thiele, Dennis J., Herskowitz, Ira
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2002
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC137878/
https://ncbi.nlm.nih.gov/pubmed/12370430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162491399
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