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Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals
Cisplatin is a chemotherapeutic drug used to treat a variety of cancers. Both intrinsic and acquired resistance to cisplatin, as well as toxicity, limit its effectiveness. Molecular mechanisms that underlie cisplatin resistance are poorly understood. Here we demonstrate that deletion of the yeast CT...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137878/ https://ncbi.nlm.nih.gov/pubmed/12370430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162491399 |
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