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Human Lamin B Contains a Farnesylated Cysteine Residue

We recently showed that HeLa cell lamin B is modified by a mevalonic acid derivative. Here we identified the modified amino acid, determined its mode of link-age to the mevalonic acid derivative, and established the derivative’s structure. A cysteine residue is modified because experiments with lami...

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Detalhes bibliográficos
Main Authors: Farnsworth, Christopher C., Wolda, Sharon L., Gelb, Michael H., Glomset, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443689/
https://ncbi.nlm.nih.gov/pubmed/2684976
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