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Lamin A, farnesylation and aging
Lamin A is a component of the nuclear envelope that is synthesized as a precursor prelamin A molecule and then processed into mature lamin A through sequential steps of posttranslational modifications and proteolytic cleavages. Remarkably, over 400 distinct point mutations have been so far identifie...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4209918/ https://ncbi.nlm.nih.gov/pubmed/21871450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2011.08.009 |
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