A filtering strategy identifies FOXQ1 as a potential effector of lamin A dysfunction

Small increases in the expression of wild-type prelamin A are sufficient to recapitulate the reduced cell proliferation and altered nuclear membrane morphology observed in cells expressing progerin, the mutant lamin A associated with progeria. We hypothesized that the manifestation of these phenotyp...

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Bibliographic Details
Main Authors: Candelario, Jose, Chen, Leng-Ying, Marjoram, Paul, Reddy, Sita, Comai, Lucio
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2012
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461344/
https://ncbi.nlm.nih.gov/pubmed/22948034
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