TGF-β-miR-34a-CCL22 Signaling-Induced Treg Cell Recruitment Promotes Venous Metastases of HBV-Positive Hepatocellular Carcinoma

Portal vein tumor thrombus (PVTT) is strongly correlated to a poor prognosis for patients with hepatocellular carcinoma (HCC). In this study, we uncovered a causative link between hepatitis B virus (HBV) infection and development of PVTT. Mechanistically, elevated TGF-β activity, associated with the...

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Detalhes bibliográficos
Main Authors: Yang, Pengyuan, Li, Qi-Jing, Feng, Yuxiong, Zhang, Yun, Markowitz, Geoffrey J., Ning, Shanglei, Deng, Yuezhen, Zhao, Jiangsha, Jiang, Shan, Yuan, Yunfei, Wang, Hong-Yang, Cheng, Shu-Qun, Xie, Dong, Wang, Xiao-Fan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443566/
https://ncbi.nlm.nih.gov/pubmed/22975373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.07.023
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