Loss of CD103+ DCs and Mucosal IL-17+ and IL-22+ Lymphocytes is Associated with Mucosal Damage in SIV Infection

HIV/SIV disease progression is associated with multifocal damage to the GI tract epithelial barrier that correlates with microbial translocation and persistent pathological immune activation but the underlying mechanisms remain unclear. Investigating alterations in mucosal immunity during SIV infect...

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Detalhes bibliográficos
Main Authors: Klatt, Nichole R., Estes, Jacob D., Sun, Xiaoyong, Ortiz, Alexandra M., Barber, John S., Harris, Levelle D., Cervasi, Barbara, Yokomizo, Lauren K., Pan, Li, Vinton, Carol L., Tabb, Brian, Canary, Lauren A., Dang, Que, Hirsch, Vanessa M., Alter, Galit, Belkaid, Yasmine, Lifson, Jeffrey D., Silvestri, Guido, Milner, Joshua D., Paiardini, Mirko, Haddad, Elias K., Brenchley, Jason M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443541/
https://ncbi.nlm.nih.gov/pubmed/22643849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2012.38
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