Loss of CD103+ DCs and Mucosal IL-17+ and IL-22+ Lymphocytes is Associated with Mucosal Damage in SIV Infection

HIV/SIV disease progression is associated with multifocal damage to the GI tract epithelial barrier that correlates with microbial translocation and persistent pathological immune activation but the underlying mechanisms remain unclear. Investigating alterations in mucosal immunity during SIV infect...

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Huvudupphovsmän: Klatt, Nichole R., Estes, Jacob D., Sun, Xiaoyong, Ortiz, Alexandra M., Barber, John S., Harris, Levelle D., Cervasi, Barbara, Yokomizo, Lauren K., Pan, Li, Vinton, Carol L., Tabb, Brian, Canary, Lauren A., Dang, Que, Hirsch, Vanessa M., Alter, Galit, Belkaid, Yasmine, Lifson, Jeffrey D., Silvestri, Guido, Milner, Joshua D., Paiardini, Mirko, Haddad, Elias K., Brenchley, Jason M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443541/
https://ncbi.nlm.nih.gov/pubmed/22643849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2012.38
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