A functionally specialized population of mucosal CD103(+) DCs induces Foxp3(+) regulatory T cells via a TGF-β– and retinoic acid–dependent mechanism

Foxp3(+) regulatory T (T reg) cells play a key role in controlling immune pathological re actions. Many develop their regulatory activity in the thymus, but there is also evidence for development of Foxp3(+) T reg cells from naive precursors in the periphery. Recent studies have shown that transform...

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Detalhes bibliográficos
Main Authors: Coombes, Janine L., Siddiqui, Karima R.R., Arancibia-Cárcamo, Carolina V., Hall, Jason, Sun, Cheng-Ming, Belkaid, Yasmine, Powrie, Fiona
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Brief Definitive Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118683/
https://ncbi.nlm.nih.gov/pubmed/17620361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070590
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