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Intestinal Inflammation Abrogates the Tolerogenic Properties of MLN CD103(+) Dendritic Cells

Intestinal CD103(+) DC promote the differentiation of Foxp3(+) T regulatory cells (Treg) from naïve CD4(+) T cells through mechanisms involving TGF-β and the dietary metabolite, retinoic acid (RA). In this study, we have analysed whether the specialized features of CD103(+) DC are conserved in colit...

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Detalles Bibliográficos
Publicado en:Eur J Immunol
Main Authors: Laffont, Sophie, Siddiqui, Karima RR, Powrie, Fiona
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6108414/
https://ncbi.nlm.nih.gov/pubmed/20432234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939957
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