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SUMO1-dependent modulation of SERCA2a in heart failure
SR Ca(2+) ATPase 2a (SERCA2a) is a critical ATPase responsible for Ca(2+) re-uptake during excitation-contraction coupling. Impaired SR Ca(2+) uptake resulting from decreased expression and reduced activity of SERCA2a is a hallmark of heart failure (HF)(1). Accordingly, restoration of SERCA2a expres...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3443490/ https://ncbi.nlm.nih.gov/pubmed/21900893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10407 |
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