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Altered sarcoplasmic reticulum calcium cycling—targets for heart failure therapy

Cardiac myocyte function is dependent on the synchronized movements of Ca(2+) into and out of the cell, as well as between the cytosol and sarcoplasmic reticulum. These movements determine cardiac rhythm and regulate excitation–contraction coupling. Ca(2+) cycling is mediated by a number of critical...

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Autori principali: Kho, Changwon, Lee, Ahyoung, Hajjar, Roger J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651893/
https://ncbi.nlm.nih.gov/pubmed/23090087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrcardio.2012.145
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