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The catalytic and the RNA subunits of human telomerase are required to immortalize equid primary fibroblasts

Many human primary somatic cells can be immortalized by inducing telomerase activity through the exogenous expression of the human telomerase catalytic subunit (hTERT). This approach has been extended to the immortalization of cell lines from several mammals. Here, we show that hTERT expression is n...

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Detalhes bibliográficos
Main Authors: Vidale, Pamela, Magnani, Elisa, Nergadze, Solomon G., Santagostino, Marco, Cristofari, Gael, Smirnova, Alexandra, Mondello, Chiara, Giulotto, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443485/
https://ncbi.nlm.nih.gov/pubmed/22797876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-012-0379-4
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