Events in the immortalizing process of primary human mammary epithelial cells by the catalytic subunit of human telomerase.

The in vitro immortalization of primary human mammary epithelial (HME) cells solely by the exogenous introduction of the catalytic subunit of human telomerase (hTERT) has been achieved. Early passage hTERT-transfected HME (T-HME) cells continuously decreased the length and density of telomeres even...

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Autors principals: Kim, Hyunggee, Farris, James, Christman, Shelly A, Kong, Byung-Whi, Foster, Linda K, O'Grady, Scott M, Foster, Douglas N
Format: Artigo
Idioma:Inglês
Publicat: 2002
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222721/
https://ncbi.nlm.nih.gov/pubmed/11978176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20011848
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