Events in the immortalizing process of primary human mammary epithelial cells by the catalytic subunit of human telomerase.

The in vitro immortalization of primary human mammary epithelial (HME) cells solely by the exogenous introduction of the catalytic subunit of human telomerase (hTERT) has been achieved. Early passage hTERT-transfected HME (T-HME) cells continuously decreased the length and density of telomeres even...

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Main Authors: Kim, Hyunggee, Farris, James, Christman, Shelly A, Kong, Byung-Whi, Foster, Linda K, O'Grady, Scott M, Foster, Douglas N
格式: Artigo
語言:Inglês
出版: 2002
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222721/
https://ncbi.nlm.nih.gov/pubmed/11978176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20011848
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