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Contribution of telomerase RNA retrotranscription to DNA double-strand break repair during mammalian genome evolution

BACKGROUND: In vertebrates, tandem arrays of TTAGGG hexamers are present at both telomeres and intrachromosomal sites (interstitial telomeric sequences (ITSs)). We previously showed that, in primates, ITSs were inserted during the repair of DNA double-strand breaks and proposed that they could arise...

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Autors principals: Nergadze, Solomon G, Santagostino, Marco Andrea, Salzano, Alberto, Mondello, Chiara, Giulotto, Elena
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246262/
https://ncbi.nlm.nih.gov/pubmed/18067655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-12-r260
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