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Contribution of telomerase RNA retrotranscription to DNA double-strand break repair during mammalian genome evolution

BACKGROUND: In vertebrates, tandem arrays of TTAGGG hexamers are present at both telomeres and intrachromosomal sites (interstitial telomeric sequences (ITSs)). We previously showed that, in primates, ITSs were inserted during the repair of DNA double-strand breaks and proposed that they could arise...

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Detalhes bibliográficos
Main Authors: Nergadze, Solomon G, Santagostino, Marco Andrea, Salzano, Alberto, Mondello, Chiara, Giulotto, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246262/
https://ncbi.nlm.nih.gov/pubmed/18067655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-12-r260
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