Contribution of telomerase RNA retrotranscription to DNA double-strand break repair during mammalian genome evolution

BACKGROUND: In vertebrates, tandem arrays of TTAGGG hexamers are present at both telomeres and intrachromosomal sites (interstitial telomeric sequences (ITSs)). We previously showed that, in primates, ITSs were inserted during the repair of DNA double-strand breaks and proposed that they could arise...

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Hlavní autoři: Nergadze, Solomon G, Santagostino, Marco Andrea, Salzano, Alberto, Mondello, Chiara, Giulotto, Elena
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246262/
https://ncbi.nlm.nih.gov/pubmed/18067655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-12-r260
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