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Flow-regulated endothelial S1P receptor-1 signaling sustains vascular development

During angiogenesis, nascent vascular sprouts fuse to form vascular networks enabling efficient circulation. Mechanisms that stabilize the vascular plexus are not well understood. Sphingosine 1-phosphate (S1P) is a blood-borne lipid mediator implicated in the regulation of vascular and immune system...

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Detalhes bibliográficos
Main Authors: Jung, Bongnam, Obinata, Hideru, Galvani, Sylvain, Mendelson, Karen, Ding, Bisen, Skoura, Athanasia, Kinzel, Bernd, Brinkmann, Volker, Rafii, Shahin, Evans, Todd, Hla, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443394/
https://ncbi.nlm.nih.gov/pubmed/22975328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.07.015
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