Role of obesity in a randomized placebo-controlled trial of difluoromethylornithine (DFMO) + sulindac for the prevention of sporadic colorectal adenomas

BACKGROUND: Chemoprevention with the polyamine-inhibitory regimen difluoromethylornithine (DFMO) + sulindac markedly reduces risk of recurrent adenoma in colorectal adenoma patients. Obesity is associated with risk of colorectal adenoma and colorectal cancer. This study investigates how obesity infl...

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Detalhes bibliográficos
Main Authors: Zell, Jason A., Lin, Bruce S., Madson, Nikki, McLaren, Christine E., Gerner, Eugene W., Meyskens, Frank L.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443348/
https://ncbi.nlm.nih.gov/pubmed/22907422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10552-012-0051-6
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