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Role of obesity in a randomized placebo-controlled trial of difluoromethylornithine (DFMO) + sulindac for the prevention of sporadic colorectal adenomas

BACKGROUND: Chemoprevention with the polyamine-inhibitory regimen difluoromethylornithine (DFMO) + sulindac markedly reduces risk of recurrent adenoma in colorectal adenoma patients. Obesity is associated with risk of colorectal adenoma and colorectal cancer. This study investigates how obesity infl...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Zell, Jason A., Lin, Bruce S., Madson, Nikki, McLaren, Christine E., Gerner, Eugene W., Meyskens, Frank L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443348/
https://ncbi.nlm.nih.gov/pubmed/22907422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10552-012-0051-6
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