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A novel ultrasensitive LC-MS/MS assay for quantification of intracellular raltegravir in human cell extracts

An assay using ultrahigh pressure liquid chromatography and mass spectrometry detection was developed and validated for measurement of the HIV integrase inhibitor raltegravir (MK-0518) in human cell extracts. The assay is designed to utilize 200 µl of 70% MeOH cell extract derived from human periphe...

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Bibliografski detalji
Glavni autori: Robbins, Brian L., Nelson, Sarah R., Fletcher, Courtney V.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443311/
https://ncbi.nlm.nih.gov/pubmed/22727807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2012.05.035
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