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Subunit organization of the membrane-bound HIV-1 envelope glycoprotein trimer

The trimeric human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (Env) spike is a molecular machine that mediates virus entry into host cells and is the sole target for virus-neutralizing antibodies. The mature Env spike results from cleavage of a trimeric gp160 precursor into three gp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mao, Youdong, Wang, Liping, Gu, Christopher, Herschhorn, Alon, Xiang, Shi-Hua, Haim, Hillel, Yang, Xinzhen, Sodroski, Joseph
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443289/
https://ncbi.nlm.nih.gov/pubmed/22864288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2351
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