Comparative Analysis of the Glycosylation Profiles of Membrane-Anchored HIV-1 Envelope Glycoprotein Trimers and Soluble gp140

The human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (Env) trimer, which consists of the gp120 and gp41 subunits, is the focus of multiple strategies for vaccine development. Extensive Env glycosylation provides HIV-1 with protection from the immune system, yet the glycans are also...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Go, Eden P., Herschhorn, Alon, Gu, Christopher, Castillo-Menendez, Luis, Zhang, Shijian, Mao, Youdong, Chen, Haiyan, Ding, Haitao, Wakefield, John K., Hua, David, Liao, Hua-Xin, Kappes, John C., Sodroski, Joseph, Desaire, Heather
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524223/
https://ncbi.nlm.nih.gov/pubmed/26018173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00628-15
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