Functional Specialization in Proline Biosynthesis of Melanoma

Proline metabolism is linked to hyperprolinemia, schizophrenia, cutis laxa, and cancer. In the latter case, tumor cells tend to rely on proline biosynthesis rather than salvage. Proline is synthesized from either glutamate or ornithine; both are converted to pyrroline-5-carboxylate (P5C), and then t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: De Ingeniis, Jessica, Ratnikov, Boris, Richardson, Adam D., Scott, David A., Aza-Blanc, Pedro, De, Surya K., Kazanov, Marat, Pellecchia, Maurizio, Ronai, Ze'ev, Osterman, Andrei L., Smith, Jeffrey W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443215/
https://ncbi.nlm.nih.gov/pubmed/23024808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045190
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