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Escape from Adaptive Conflict follows from weak functional trade-offs and mutational robustness

A fundamental question in molecular evolution is how proteins can adapt to new functions while being conserved for an existing function at the same time. Several theoretical models have been put forward to explain this apparent paradox. The most popular models include neofunctionalization, subfuncti...

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Detalhes bibliográficos
Main Authors: Sikosek, Tobias, Chan, Hue Sun, Bornberg-Bauer, Erich
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443171/
https://ncbi.nlm.nih.gov/pubmed/22927372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115620109
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