Mouse lipin-1 and lipin-2 cooperate to maintain glycerolipid homeostasis in liver and aging cerebellum

The three lipin phosphatidate phosphatase (PAP) enzymes catalyze a step in glycerolipid biosynthesis, the conversion of phosphatidate to diacylglycerol. Lipin-1 is critical for lipid synthesis and homeostasis in adipose tissue, liver, muscle, and peripheral nerves. Little is known about the physiolo...

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Dades bibliogràfiques
Autors principals: Dwyer, Jennifer R., Donkor, Jimmy, Zhang, Peixiang, Csaki, Lauren S., Vergnes, Laurent, Lee, Jessica M., Dewald, Jay, Brindley, David N., Atti, Elisa, Tetradis, Sotirios, Yoshinaga, Yuko, De Jong, Pieter J., Fong, Loren G., Young, Stephen G., Reue, Karen
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443145/
https://ncbi.nlm.nih.gov/pubmed/22908270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205221109
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