Mouse lipin-1 and lipin-2 cooperate to maintain glycerolipid homeostasis in liver and aging cerebellum

The three lipin phosphatidate phosphatase (PAP) enzymes catalyze a step in glycerolipid biosynthesis, the conversion of phosphatidate to diacylglycerol. Lipin-1 is critical for lipid synthesis and homeostasis in adipose tissue, liver, muscle, and peripheral nerves. Little is known about the physiolo...

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Autores principales: Dwyer, Jennifer R., Donkor, Jimmy, Zhang, Peixiang, Csaki, Lauren S., Vergnes, Laurent, Lee, Jessica M., Dewald, Jay, Brindley, David N., Atti, Elisa, Tetradis, Sotirios, Yoshinaga, Yuko, De Jong, Pieter J., Fong, Loren G., Young, Stephen G., Reue, Karen
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2012
Materias:
PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443145/
https://ncbi.nlm.nih.gov/pubmed/22908270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205221109
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