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Sites of genetic instability in mitosis and cancer
Certain chromosomal regions called common fragile sites are prone to difficulty during replication. Many tumors have been shown to contain alterations at fragile sites. Several models have been proposed to explain why these sites are unstable. Here we describe work to investigate models of fragile s...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3442947/ https://ncbi.nlm.nih.gov/pubmed/22954212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2012.06592.x |
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