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An anti-let-7 sponge decoys and decays endogenous let-7 functions

The let-7 family contains 12 members, which share identical seed regions, suggesting that they may target the same mRNAs. It is essential to develop a means that can regulate the functions of all members. Using a DNA synthesis technique, we have generated an anti-let-7 sponge aiming to modulate the...

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Detalhes bibliográficos
Main Authors: Yang, Xiangling, Rutnam, Zina Jeyapalan, Jiao, Chunwei, Wei, Duo, Xie, Yizhen, Du, Jun, Zhong, Ling, Yang, Burton B.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442920/
https://ncbi.nlm.nih.gov/pubmed/22871741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21503
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