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Relative Movements of Transmembrane Regions at the Outer Mouth of the Cystic Fibrosis Transmembrane Conductance Regulator Channel Pore during Channel Gating

Multiple transmembrane (TM) segments line the pore of the cystic fibrosis transmembrane conductance regulator Cl(−) channel; however, the relative alignment of these TMs and their relative movements during channel gating are unknown. To gain three-dimensional structural information on the outer pore...

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Detalhes bibliográficos
Main Authors: Wang(王, Wuyang, 午阳), Linsdell, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442544/
https://ncbi.nlm.nih.gov/pubmed/22843683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.385096
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