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Relative Movements of Transmembrane Regions at the Outer Mouth of the Cystic Fibrosis Transmembrane Conductance Regulator Channel Pore during Channel Gating

Multiple transmembrane (TM) segments line the pore of the cystic fibrosis transmembrane conductance regulator Cl(−) channel; however, the relative alignment of these TMs and their relative movements during channel gating are unknown. To gain three-dimensional structural information on the outer pore...

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Opis bibliograficzny
Główni autorzy: Wang(王, Wuyang, 午阳), Linsdell, Paul
Format: Artigo
Język:Inglês
Wydane: American Society for Biochemistry and Molecular Biology 2012
Hasła przedmiotowe:
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442544/
https://ncbi.nlm.nih.gov/pubmed/22843683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.385096
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