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Relative Movements of Transmembrane Regions at the Outer Mouth of the Cystic Fibrosis Transmembrane Conductance Regulator Channel Pore during Channel Gating

Multiple transmembrane (TM) segments line the pore of the cystic fibrosis transmembrane conductance regulator Cl(−) channel; however, the relative alignment of these TMs and their relative movements during channel gating are unknown. To gain three-dimensional structural information on the outer pore...

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Hlavní autoři: Wang(王, Wuyang, 午阳), Linsdell, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442544/
https://ncbi.nlm.nih.gov/pubmed/22843683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.385096
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