Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA

Lipid nanoparticles (LNP) are the leading systems for in vivo delivery of small interfering RNA (siRNA) for therapeutic applications. Formulation of LNP siRNA systems requires rapid mixing of solutions containing cationic lipid with solutions containing siRNA. Current formulation procedures employ m...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Belliveau, Nathan M, Huft, Jens, Lin, Paulo JC, Chen, Sam, Leung, Alex KK, Leaver, Timothy J, Wild, Andre W, Lee, Justin B, Taylor, Robert J, Tam, Ying K, Hansen, Carl L, Cullis, Pieter R
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2012
विषय:
Original Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442367/
https://ncbi.nlm.nih.gov/pubmed/23344179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2012.28
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