DEAD-box protein DDX3 associates with eIF4F to promote translation of selected mRNAs

Here, we have characterized a step in translation initiation of viral and cellular mRNAs that contain RNA secondary structures immediately at the vicinity of their m(7)GTP cap. This is mediated by the DEAD-box helicase DDX3 which can directly bind to the 5′ of the target mRNA where it clamps the ent...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Soto-Rifo, Ricardo, Rubilar, Paulina S, Limousin, Taran, de Breyne, Sylvain, Décimo, Didier, Ohlmann, Théophile
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442272/
https://ncbi.nlm.nih.gov/pubmed/22872150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.220
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