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miRNA repression of translation in vitro takes place during 43S ribosomal scanning

microRNAs (miRNAs) regulate gene expression at multiple levels by repressing translation, stimulating deadenylation and inducing the premature decay of target messenger RNAs (mRNAs). Although the mechanism by which miRNAs repress translation has been widely studied, the precise step targeted and the...

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Detalhes bibliográficos
Main Authors: Ricci, Emiliano P., Limousin, Taran, Soto-Rifo, Ricardo, Rubilar, Paulina S., Decimo, Didier, Ohlmann, Théophile
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592420/
https://ncbi.nlm.nih.gov/pubmed/23161679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1076
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