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Electrophilic Derivatives of Purines as Irreversible Inhibitors of A(1) Adenosine Receptors

Functionalized congeners derived from 1,3-dipropyl-8-phenylxanthine and from N(6)-phenyladenosine were derivatized to contain electrophilic groups (isothiocyanate, N-hydroxysuccinimide ester, maleimide, sulfonyl chloride, or α-haloacyl group) capable of reaction with nucleophiles on biopolymers. The...

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Main Authors: Jacobson, Kenneth A., Barone, Suzanne, Kammula, Udai, Stiles, Gary L.
格式: Artigo
語言:Inglês
出版: 1989
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442263/
https://ncbi.nlm.nih.gov/pubmed/2709373
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