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Trifunctional Agents as a Design Strategy for Tailoring Ligand Properties: Irreversible Inhibitors of A(1) Adenosine Receptors
The 1,3-phenylene diisothiocyanate conjugate of XAC (8-[4-[[[[(2-aminoethyl)amino]carbonyl]methyl]-oxy]phenyl]-l,3-dipropylxanthine, a potent A(1) selective adenosine antagonist) has been characterized as an irreversible inhibitor of A(1) adenosine receptors. To further extend this work, a series of...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3427756/ https://ncbi.nlm.nih.gov/pubmed/1868116 |
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