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Dnmt1 Expression in Pre- and Postimplantation Embryogenesis and the Maintenance of IAP Silencing

The methylation of intracisternal A-type particle (IAP) sequences is maintained during mouse embryogenesis. Methylation suppresses IAP expression and the potential for mutagenesis by retrotransposition, but it is not clear how methylation of these elements is maintained during the embryonic stages w...

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Detalhes bibliográficos
Main Authors: Gaudet, F., Rideout, W. M., Meissner, A., Dausman, J., Leonhardt, H., Jaenisch, R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC344181/
https://ncbi.nlm.nih.gov/pubmed/14749379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.4.1640-1648.2004
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