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Enhanced transfection of tumor cells in vivo using “Smart” pH-sensitive TAT-modified pegylated liposomes

Liposomes have been prepared loaded with DNA (plasmid encoding for the green fluorescent protein, GFP) and additionally modified with TATp and PEG, with PEG being attached to the liposome surface via both pH-sensitive hydrazone and non-pH-sensitive bonds. The pGFP-loaded liposomal preparations have...

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Detalhes bibliográficos
Main Authors: Kale, Amit A., Torchilin, Vladimir P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441052/
https://ncbi.nlm.nih.gov/pubmed/17671900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10611860701498203
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