Cell transfection in vitro and in vivo with nontoxic TAT peptide-liposome–DNA complexes

Liposomes modified with TAT peptide (TATp-liposomes) showed fast and efficient translocation into the cell cytoplasm with subsequent migration into the perinuclear zone. TATp-liposomes containing a small quantity (≤10 mol %) of a cationic lipid formed firm noncovalent complexes with DNA. Here, we pr...

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Bibliographic Details
Main Authors: Torchilin, Vladimir P., Levchenko, Tatyana S., Rammohan, Ram, Volodina, Natalia, Papahadjopoulos-Sternberg, Brigitte, D'Souza, Gerard G. M.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2003
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC149943/
https://ncbi.nlm.nih.gov/pubmed/12571356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0435906100
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