Enhanced binding and killing of target tumor cells by drug-loaded liposomes modified with tumor-specific phage fusion coat protein

AIM: To explore cancer cell-specific phage fusion pVIII coat protein, identified using phage display, for targeted delivery of drug-loaded liposomes to MCF-7 breast cancer cells. MATERIAL & METHODS: An 8-mer landscape library f8/8 and a biopanning protocol against MCF-7 cells were used to select...

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Main Authors: Wang, Tao, D’Souza, Gerard GM, Bedi, Deepa, Fagbohun, Olusegun A, Potturi, L Prasanna, Papahadjopoulos-Sternberg, Brigitte, Petrenko, Valery A, Torchilin, Vladimir P
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914609/
https://ncbi.nlm.nih.gov/pubmed/20528452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.10.30
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