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Regulation of Insulin-Like Growth Factor Signaling by Yap Governs Cardiomyocyte Proliferation and Embryonic Heart Size

The Hippo signaling pathway regulates growth of the heart and other tissues. Hippo pathway kinases influence the activity of various targets, including the transcriptional coactivator Yap, but the specific role of Yap in heart growth has not been investigated. We show that Yap is necessary and suffi...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Xin, Mei, Kim, Yuri, Sutherland, Lillian B., Qi, Xiaoxia, McAnally, John, Schwartz, Robert J., Richardson, James A., Bassel-Duby, Rhonda, Olson, Eric N.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440872/
https://ncbi.nlm.nih.gov/pubmed/22028467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2002278
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