Lifetimes of intermediates in the β-sheet to α-helix transition of β-lactoglobulin by using a diffusional IR mixer

The extremely slow α-helix/β-sheet transition of proteins is a crucial step in amylogenic diseases and represents an internal rearrangement of local contacts in an already folded protein. These internal structural rearrangements within an already folded protein are a critical aspect of biological ac...

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Hauptverfasser: Kauffmann, Ekkehard, Darnton, Nicholas C., Austin, Robert H., Batt, Carl, Gerwert, Klaus
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2001
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC34407/
https://ncbi.nlm.nih.gov/pubmed/11371608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.101122898
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