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Immunohistochemical analysis of integrins αvβ3, αvβ5 and α5β1, and their ligands, fibrinogen, fibronectin, osteopontin and vitronectin, in frozen sections of human oral head and neck squamous cell carcinomas

Integrins mediate the interaction of cells with the extracellular matrix and are believed to be involved in tumor cell survival and metastasis, and in tumor angiogenesis. We used immunohistochemistry of fresh-frozen human tumor tissues to analyze the presence of integrins αvβ3, αvβ5 and α5β1, which...

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Autors principals: FABRICIUS, EVA-MARIA, WILDNER, GUSTAV-PAUL, KRUSE-BOITSCHENKO, UTE, HOFFMEISTER, BODO, GOODMAN, SIMON L., RAGUSE, JAN-DIRK
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440681/
https://ncbi.nlm.nih.gov/pubmed/22977464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2010.171
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