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Comparing the expression of integrins αvβ3, αvβ5, αvβ6, αvβ8, fibronectin and fibrinogen in human brain metastases and their corresponding primary tumors

Aims: To evaluate the expression of αv-series integrins in brain metastases. Inhibitors targeting these integrins are being tested for their therapeutic potential. Material and Method: The extracellular regions of the αvβ3, αvβ5, αvβ6, αvβ8, the cytoplasmic domain of β3, the αv-chain, and the ECM mo...

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Autores principales: Schittenhelm, Jens, Klein, Annemarie, Tatagiba, Marcos S, Meyermann, Richard, Fend, Falko, Goodman, Simon L, Sipos, Bence
Formato: Artigo
Lenguaje:Inglês
Publicado: e-Century Publishing Corporation 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843253/
https://ncbi.nlm.nih.gov/pubmed/24294359
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